A novel ketone olefination via organozinc reagents in the presence of diphenyl phosphite.
نویسندگان
چکیده
Carbonyl compounds react with organozinc reagents in the presence of diphenyl phosphite to give the corresponding olefins. A variety of 1,3-dienes and unsaturated esters were obtained in moderate to excellent yields under mild conditions.
منابع مشابه
A novel and efficient method for the olefination of carbonyl compounds with Grignard reagents in the presence of diethyl phosphite.
The widely available carbonyl compounds react with Grignard reagents in the presence of diethyl phosphite to give the corresponding olefins in good to excellent yields: A range of conjugated dienes, terminal olefins, multisubstituted-alkenes and conjugated enynes could be readily obtained by the method in mild conditions.
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The synthesis of unsymmetrical diaryl ketones via the Fukuyama coupling of thioesters and organozinc reagents is described. Typically, the synthesis of diaryl ketones using this methodology provides low yields. The simple complex, Pd(dba)(2), was found to convert a variety of aryl thioesters to diaryl ketones in good yields.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 14 شماره
صفحات -
تاریخ انتشار 2012